Sunday, 13 January 2013

3. Erectile Dysfunction. Research from W. Australia and S. Korea. Moderate drinkers’ have better sex lives than teetotallers. Benefits of ginseng berry extract on sexual function.

Ginseng berry extract and alcohol are beneficial for sexual function in men with sexual dysfunction, according to studies from S. Korea in 2013 and W. Australia in 2009.

1. Scientists in Seoul, S Korea reported favourably on their findings in April 2013 on ginseng   berry extract given to men with erectile dysfunction.

 2013 Mar-Apr;25(2):45-50. doi: 10.1038/ijir.2012.45. Epub 2012 Dec 20.

Effects of Korean ginseng berry extract on sexual function in men with erectile dysfunction: a multicenter, placebo-controlled, double-blind clinical study.


Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, South Korea.
Ginseng is beneficial for many aspects of human physiology, including sexual function. In this study, we have evaluated the efficacy and safety of an extract of ginseng berry, which has a ginsenoside profile distinct from other parts of the plant, on sexual function in men with erectile dysfunction. In all, 119 men with mild-to-moderate ED participated in a multicenter, randomized, double-blind, parallel, placebo-controlled clinical study. They were administered 4 tablets of either standardized Korean ginseng berry (SKGB, 350 mg ginseng berry extract per tablet), or placebo, daily, for 8 weeks. Efficacy was assessed with the International Index of Erectile Function (IIEF)-15 and premature ejaculation diagnostic tool (PEDT) at the end of the 4th and 8th week. We observed that the total and each of the individual domain scores of IIEF-15 increased from 40.95 ± 7.05 to 46.19 ± 12.69 significantly in the SKGB by the 8th week (P<0.05). The erectile function domain of IIEF changed slightly from 17.17 ± 2.57 to 18.59 ± 5.99 in the SKGB group by the 8th week (P<0.05). In addition, PEDT scores significantly improved from 9.14 ± 4.57 to 7.97 ± 4.4 and 7.53 ± 4.26 in the SKGB group after 4 and 8 weeks of treatment (P<0.05). Safety markers including hormone and lipid in the blood were assessed at the end of the 4th and 8th week and they remained unchanged. Oral administration of the SKGB extract improved all domains of sexual function. It can be used as an alternative medicine to improve sexual life in men with sexual dysfunction.

Keogh Institute for Medical Research
2. The Keogh Institute for Medical Research in Western Australia found alcohol had beneficial effects on men suffering from erectile dysfunction. Clair Weaver's article  on the subject in the Sydney Sunday Telegraph on 25 January 2009  is reproduced in full below:

“It gives the phrase "a stiff drink" a whole new meaning: Australian researchers have made the surprise discovery that alcohol improves, rather than damages, men's performance in the bedroom.

They hope the finding, which flies in the face of conventional belief, will reassure men who worry about the effects of drinking on their sex lives.

Until now, it has been widely believed alcohol consumption could cause erectile dysfunction, commonly called "brewer's droop''.But a study of 1580 Australian men has shown the reverse may be true, with drinkers reporting as many as 30 per cent fewer problems than teetotallers.

Even binge drinkers had lower rates of erectile dysfunction than those who never drank, although this type of drinking can cause other health problems.

Lead study author Dr Kew-Kim Chew, of Western Australia's Keogh Institute for Medical Research, told The Sunday Telegraph men who drank within safe guidelines appeared to have the best erectile function.

"We found that, compared to those who have never touched alcohol, many people do benefit from some alcohol, including some people who drink outside the guidelines,'' Dr Chew said.

Dr Chew said he had patients with erectile dysfunction who had been told to stop drinking completely.

The latest finding should prevent them compounding the problem by feeling ``guilty and stressed'' about present or past drinking, he said.

After other risk factors were excluded, weekend drinkers, high-risk drinkers and those who exceeded alcohol-intake guidelines had lower rates of erectile dysfunction than those who drank one day a week or less. Ex-drinkers, however, had the highest risk.

"Although alcohol may increase sexual desire through disinhibition, the slang term ``brewer's droop'' captures its reputation as a risk factor for decreased sexual performance,'' the study says.

"These findings suggest a favourable association between low-risk alcohol drinking and (positive) erectile function.''

Low-risk drinking for men is defined as up to four drinks a day for up to five days a week, according to National Health and Medical Research Council guidelines.

The study, which will be published in the Journal of Sexual Medicine, concludes there is ``no justification'' to advise men with erectile dysfunction who drink moderately to stop or reduce their drinking.

Earlier parts of the study, however, confirm that men who smoke or have heart disease are at higher risk of erectile dysfunction.

Dr Chew will present his findings at an international conference in April”.

Sir Charles Gairdner Hospital
Keogh Institute for Medical Research

2 Verdun Street, Nedlands 
WA 6009, Australia